Wellbutrin SR is a pharmaceutical prescription antidepressant which acts directly on the brain and other nerve cells. It is also used to treat ADHD (Attention Deficit Disorder), Bipolar depression, chronic fatigue syndrome, cocaine addiction, nicotine addiction, and lower back pain. Also, aids in quitting smoking (identical to Zyban). It is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents.